Allium
longicuspis and Allium tuncelianum
have long been regarded as the wild ancestors
of modern garlic. Both are widely distributed
throughout Turkey and A. tuncelianum
is of particular interest as it is a fully fertile
species. Both A. tuncelianum and A.
longicuspis smell of garlic when crushed
and are used locally as a substitute for the
modern cultivated forms of A. sativum.
Recent
genetic research by Meryem
Ipek and Philipp Simon has suggested that
A. sativum and A. longicuspis
should no longer be considered as genetically
distinct and Brian Mathew, in his book A
Review of Allium section Allium, puts
forward the possibility that A. tuncelianum
is the wild ancestor of both A. longicuspis
and A. sativum. A. tuncelianum is endemic to the
region of Tunceli in central Turkey and is
collected and consumed locally.
The continued collection from the wild has
led to concerns about its survival as a wild
species and as a result, the United Nations
Development Programme awarded a small grant
to the Accessible Life Association (UYD) who
used the money to determine the cultivation
conditions of the plant as well as market
suitability, size and feasibility.
The
project brought together some of the poorest
farmers in the most underdeveloped region of
Turkey with the aim of making them aware of
the global importance of the plant and the need
to protect it. It was hoped that small-scale
cultivation would not only help to preserve
the plant in the wild but might also lead to
the development of a new cash crop for the region’s
farmers.
The cultivation trials were carried out both
in laboratory conditions and on a piece of land
bought by 120 local farmers and were successfully
completed in October 2003.
Garlic
Fights Back Against MRSA
Researchers
at the Chungshan
Medical University Hospital in Taiwan have spent
many years investigating the antimicrobial properties
of garlic compounds and recent publications in the
Journal of
Medical Microbiology and the Journal
of Antimicrobial Chemotherapy show the effectiveness
of some compounds against a number of bacteria,
and in particular methicillin-resistant Staphylococcus
aureus (MRSA).
In 2001 the Journal of Medical Microbiology published
a paper by Shyh-Ming Tsao and Mei-Chin Yin of the
Department of Internal Medicine entitled ‘In-vitro
antimicrobial activity of four diallyl sulphides
occurring naturally in garlic and Chinese leek oils’.
This work reported on the effectiveness of four
naturally occurring diallyl sulphides against Staphylococcus
aureus, methicillin-resistant S. aureus
(MRSA), three Candida species and
three Aspergillus species. The results
showed that diallyl disulphide, diallyl trisulphide,
diallyl tetrasulphide and the oils rich in these
sulphides may have a role in the prevention or treatment
of infections.
It
is now thought that MRSA causes an estimated
2,000 deaths in UK hospitals each year mainly
through secondary infection of surgical wounds.
Though MRSA organisms can live harmlessly in
humans and are carried in the nasal passages
and on the skin, they can cause fatal infection
in immunologically-suppressed patients, the
elderly, the young and those with surgical implants.
Doctors have become increasingly alarmed over
the past few months by the emergence in UK hospitals
of new generations of resistant strains of MRSA
known as VISAs, and GISAs (Vancomycin or Glycopeptide
resistant Staphylococcus aureus). MRSA
has also become endemic in many hospitals, especially
in London and the South-East, prompting the
NHS to review its hygiene procedures.
Following
on from the work undertaken by Tsao and Yin
in Taiwan, microbiologist Dr Ron Cutler of the
University of
East London (UEL) has undertaken clinical
trials in the UK with some degree of success.
His research on the laboratory effects of allicin
on glycopeptide resistant Staphylococcus
aureus (GISA) was presented in part at
the Institute
of Biomedical Scientists congress in Birmingham,
October 2003, and subsequently published in
August 2004 the British
Journal of Biomedical Science. (Abstract)